@techreport{TR-IC-07-26, number = {IC-07-26}, author = {F.P.G.~Bergo and G.C.S.~Ruppert and L.F.~Pinto and A.X.~Falc{\~{a}}o}, title = {Fast and Robust Mid-sagittal Plane Location in {3D} {MR} Images of the Brain}, month = {August}, year = {2007}, institution = {Institute of Computing, University of Campinas}, note = {In English, 12 pages. \par\selectlanguage{english}\textbf{Abstract} Extraction of the mid-sagittal plane (MSP) is an important step for brain image registration and asymmetry analysis. We present a fast MSP extraction method for 3D MR images, which is based on automatic segmentation of the brain and on heuristic maximization of cerebro-spinal fluid within the MSP. The method is shown to be robust to severe anatomical asymmetries between the hemispheres, caused by surgical procedures and lesions. The experiments used 64 MR images (36 pathological, 20 healthy, 8 synthetic) and the method found an acceptable approximation of the MSP in all images with a mean time of 60.0 seconds per image. } }